Tirzepatide generally produces faster and greater weight loss, but it also costs more through MEDVi and may produce stronger initial side effects during the titration phase
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eNeurologicalSci (2020) 21:100270
From the above, it is clear that drugs with short half-lives reach steady state quicker and are washed out sooner, and drugs with long half-lives reach steady state more slowly and take longer to wash out