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doi:10.1080/08998280.2019.1641045

Blood-based biomarkers in Alzheimer's disease: advancing non-invasive diagnostics and prognostics

Data indicates a denitive correlation between low glutathione levels and decreased brain health, as it is widely regarded as the most critical brain antioxidant

These observations raise an intriguing possibility that insults in HSCs over the lifespan are a driver of maladaptive trained immunity, resulting in aging-associated inflammation and functional decline of distant tissues

However, as we age or face increased stress, our natural production of glutathione may begin to decline