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It can trigger cellcycle arrest, repair or apoptosis

Extracellular signal-regulated kinase (ERK), a MAP kinase family that modifies gene expression through the phosphorylation of a variety of transcription factors, is the most frequent pathway associated with the control of cell proliferation

Analogs were designed and synthesized with the goal of stabilizing helical structure and improving favorable intermolecular interactions (Supplementary Figs

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