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Dziki poczeniu krtkiej sekwencji peptydowej z jonem miedzi zwizek ten stanowi uyteczny model do bada nad metalopeptydami oraz ich znaczeniem w biologii komrkowej

Synthesis of Glutathione and Analogues Compounds 1.62 (D-cysteine modified), 1.63 (D-glutamic acid modified), 1.64 (both D-cysteine and D-glutamic acid modified), 1.65 ( N -methylated glycine), 1.70 ( N -methylated cysteine), and 1.71 ( N -methylated glutamic acid) were synthesised, characterised, and screened in comparison to Compound 1.61 (glutathione synthesised under the same conditions) and commercially available glutathione

However, the pro-vascular effects of IGFBP seem to be independent of IGF, which provides a new direction for further exploration of the relationship between the IGF system and tumor angiogenesis

Our results also indicate that the cleavage is not restricted to the N- or C-terminus of proteins as we detected selective proteolysis also for internal sites

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