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Doses of pyridoxine as low as 5-10 mg can antagonize levodopas effect if carbidopa is not present, so caution is warranted and any supplemental B beyond the nutritional dose should be under medical guidance

Peptides modulate pain indirectly through inflammation reduction, tissue repair, and nerve regeneration

Cognitive Benefits: Evidence suggests that vitamin B12 injections can enhance memory, attention, and processing speed, especially in individuals with cognitive impairment due to deficiency

Pregnant and breastfeeding individuals have increased requirements for many B vitamins, and indeed these vitamins are routinely included in prenatal supplements

Of note, the effect of supplementation may not persist after the period of supplementation