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Results, safety, and dosing remain unproven in human populations

Headache, particularly at initiation Mild anxiety or restlessness with some compounds Nasal irritation (intranasal administration) Sleep disturbance if dosed too close to bedtime Rare: Mood changes or emotional lability Dihexa (PNB-0408, N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a potent hepatocyte growth factor (HGF) receptor agonist originally developed at Washington State University

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Annu Rev Biochem 52:711760 Murata K, Tani K, Kato J, Chibata I (1981) Glycolytic pathway as an ATP generation system and its application to the production of glutathione and NADP

You might experience burning in the forearm and difficulty gripping things or straightening your arm