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"In both age groups, the last dispensed prescription in 2023 was most commonly for injectable semaglutide [Ozempic] for Type 2 diabetes," Lee's group noted

Recovery was molecule-specific, rather than uniform, reinforcing the sense that resolution would be staggered, rather than decisive

There may also be a connection to sex hormones because most lupus patients are women of reproductive age with high levels of estrogen and low levels of progesterone, a hormone that supports pregnancy (x)

It is unclear to what extent the reduction in lean mass is attributable to loss of skeletal muscle mass per se, which comprises only one component of total body lean mass in mice, but the lack of effect on fat mass is consistent with the reported paucity of IGF-1Rs on mature adipocytes