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Take home message Three oral GLP-1 medications are relevant to UK consumers in 2026

Randomized trials in adults with obesity and women with PCOS further reveal decreases in liking and increased aversion toward sweet and fatty foods, supporting a shift in the hedonic valuation of food rather than a primary alteration in peripheral taste sensitivity (175180)

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Berberine side effects tend to be gastrointestinal, such as mild constipation or diarrhea

In treatment of Type 2 diabetes, these treatments have demonstrated a 5-10% weight loss in patients