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the psychological toll is equally devastating

Studies show 8-mL injections deliver superior outcomes versus 4-mL volumes

Notably, despite theoretical concerns about increased infection risk due to neutrophil protease inhibition, no signal for increased severe infections emerged

The clinical evidence linking GLP-1 medications to persistent gastroparesis remains evolving and somewhat controversial

doi: 10.1038/nrrheum.2011.207 Summary Keywords gout, bile acid metabolism, uric acid homeostasis, NLRP3 inflammasome, gut-joint axis, FXR antagonists Citation Sun H, Yang L, Sun Y, Zhang X, Sun X, Zhao X, Sun H, Zhang Q, Yan G and Wang X (2025) Dysregulated bile acid metabolism as a novel player in gout progression: emerging therapeutic strategies