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To stay ahead of this shifting environment, pharma companies should consider the following imperatives: Massive patient drop-off undermines obesity GLP-1 uptake: Despite strong demand, only 10% of obesity patients persist with therapy after one year

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The 100mg strength provides a larger quantity option for research applications requiring more material than the standard 50mg size

The conversation is rightly evolving beyond utilization management and short-term cost containment toward a more comprehensive strategy focused on clinical oversight, nutrition support, patient engagement, adherence, and measurable outcomes