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More to learn about the effects of semaglutide (GLP-1 RA) Science is still learning about how semaglutide (GLP-1 RA) drugs affect the body, including how they may impact the way you respond to food

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An early transient eGFR decrease associated with a transient decrease in albuminuria was also observed in overweight/obese participants without DM in the SELECT trial [20]

In a head-to-head trial against semaglutide (the SURPASS-2 trial), tirzepatide produced significantly greater weight loss, with participants taking the highest dose of tirzepatide losing an average of 11.2 kg (24.7 lbs), compared to 5.7 kg (12.5 lbs) for those taking semaglutide 1 mg

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