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Association of halo nevus/i and vitiligo in childhood: a retrospective observational study

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Thus, HLA-DR15 may result in impaired activation of the HLA-II-mediated CD4 T response, increased viral load/EBV latency cells, increased levels of anti-EBV nuclear antigen 1 (anti-EBNA-1) antibodies, and expansion of CD8 T cells, which may be less effective inducing viral clearance (121, 122)