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54 A less common mutation of the CBS gene is the cause of a rare genetic disease called homocystinuria, marked by low or no activity of CBS, massive elevation of blood and urine homocysteine levels, and numerous serious complications

By targeting both GIP and GLP-1 receptors, Tirzepatide enhances insulin secretion and reduces glucagon levels, leading to better glycemic control

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The increased relative abundance of Bacteroides dorei and Roseburia inulinivorans may indicate a lower inflammatory status of GLP-1 RA responders