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Description

Jones, R., Mann, T

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The standard approach is to probability-weight the exclusivity cliff: assign a probability to each listed patents survival through the litigation period and calculate the expected loss-of-exclusivity date as a probability-weighted average across the patent portfolio

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Under conditions of reduced caloric intake, AMPK-mediated suppression of anabolic pathways, combined with diminished amino acid availability, may constrain mechanistic target of rapamycin (mTOR) signaling and translational capacity [52, 88]

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