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Kosower et al [11] had previously reported that monobromobimane (a derivative of 1,5-diazobicyclo[3,3,0] actadiendiones) and non fluorescent compound with an electrophilic site, slowly reacted with glutathione to form fluorescent glutathione conjugate and that the reaction might be catalysed by glutathione transferase

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Although GLP-1RAs exert beneficial effects by delaying gastric emptying, enhancing satiety, and reducing caloric intakemechanisms that predominantly promote FM reductionthey are also associated with a loss of lean mass, particularly in the context of substantial weight loss where muscle preservation is critical for metabolic health [77]

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