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Because it degrades in blood in a pathway involving amino-peptidases, it may not be suitable for people who take medications that inhibit or are metabolized by peptidases (e.g., captopril, a treatment for hypertension).4 Also, based on what we know about other therapeutic peptides, we would say DSIP is contraindicated for women who are pregnant or breastfeeding as well as people with a personal history of cancer

However, severe reactions such as difficulty breathing, facial swelling, and anaphylaxis occur in rare cases, indicating a serious allergic reaction that requires immediate medical attention