We have focused on O 2 -(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate (JS-K) as an example of diazeniumdiolate prodrugs with potential for cancer chemotherapy
The participants were: Meghan Azad, PhD - Director of THRiVE & MILC Bridget McGann - Biological Anthropologist & Knowledge Translation Consultant at THRiVE & MILC Karinne Cardoso Muniz, MD - Neonatologist & MSc Student at THRiVE & MILC Christina Raimondi, MD, IBCLC, NABBLM-C - MILC member & Co-Founder/CEO at the Winnipeg Breastfeeding Centre Sanoji Wijenayake, PhD - MILC member & Assistant Professor at University of Winnipeg Ryan Pace, PhD - Assistant Director of the Biobehavioral Lab at the Health Microbiomes Institute, University of South Florida Emma Bhakuni - Neonatal Clinical Support Worker, NHS Foundation Trust in the UK Raha Afshariani, MD, IBCLC - Canadian Lactation Consultant Association
The apparatus consists of a white acrylic board with two open arms (dimensions: 25 cm 5 cm 0.5 cm), two closed arms (dimensions: 25 cm 5 cm 16 cm), and a central open platform (dimensions: 5 cm 5 cm)
ROS continues to activate upstream mitogen-activated protein kinases, and then phosphorylates JNK
The redox role of G6PD in cell growth, cell death, and cancer