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Front Cell Dev Biol 21(9):637162 Stolwijk JM, Stefely JA, Veling MT et al (2021) Red blood cells contain enzymatically active GPx4 whose abundance anticorrelates with hemolysis during blood bank storage

Invest Ophthalmol Vis Sci 46:431119, PMID: 16249513 Robillard JM, Gordon GR, Choi HB, Christie BR, MacVicar BA (2011) Glutathione restores the mechanism of synaptic plasticity in aged mice to that of the adult

Interestingly, GSH deficiency upregulates genes associated with NAFLD (Fig

At a molecular level, smoking affects key signaling pathways such as nuclear factor-kappa B (NF-kB) and mitogen-activated protein kinases (MAPK) and induces epigenetic modifications like DNA methylation and histone modification [22]

Along with chemotherapy drugs, it can promote cell repair and flush out toxic substances