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This finding is consistent with clinical observations that some patients with tinnitus exhibit clinically normal audiograms 14,15

MECHANISTIC SPECULATION: WHAT THE FRAMEWORK CLAIMS Mechanistic speculation = inferring possible antiaging effects from models, genes, and expression patterns rather than from clinical outcomes

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It has been reported that D-2HG is released by malignant cells and accumulated in the extracellular space, then it is taken up by T lymphocytes, limiting their capacity to mediate antitumoral immune response (Fig

A number of tissues contain significant concentrations of ALC but these decrease as we age and there is evidence that dietary supplementation can address these shortfalls