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GLP-1 receptor agonists are a class of medications that mimic a hormone naturally produced in your gut called glucagon-like peptide-1

Speak to your physician if you think you may be experiencing bad side effects or need the Wellbutrin dose adjusted

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This was not observed with GLP-1 or GLP-1/GIP agonists and may be related to the glucagon component Higher discontinuation rates than semaglutide or tirzepatide, though some discontinuations were due to "perceived excessive weight loss" in patients with lower BMI The higher GI burden correlates with retatrutide's higher weight loss (28.7%) Orforglipron# Orforglipron is an oral non-peptide GLP-1 agonist