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Low GSH, neutrophil infiltration, myeloperoxidase activity and inflammation increase oxidative stress overwhelming the antioxidant defense, and hypochlorous acid mediated GSH oxidation and its attachment to proteins contribute to further GSH deficiency (114)

Chabory E, Damon C, Lenoir A et al

Modulating parameters such as size, shape, surface charge, stiffness, and surface chemical composition can alter interactions with immune cells, including T cells, dendritic cells (DCs), and macrophages, expanding their applicability for immunological regulation [27]

We might therefore predict that other metabolites would also exhibit reductions correlated with reductions in glutathione and glutamate