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But excessive or prolonged inflammation becomes destructive

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20.29 The melanocytes within a proliferative nodule have vesicular nuclei, scattered nucleoli, and increased mitotic activity Intradermal congenital melanocytic nevi demonstrate similar histologic features within the dermis to those seen in compound nevi

That approach improves interpretability, reduces unnecessary escalation, and keeps the work anchored in a research-only context where safety controls and documentation are part of the protocol, not an afterthought