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The dual-target mechanism of ACE not only circumvents the problem of compensatory drug resistance of single-target inducers, but also achieves highly efficient and low-toxicity tumor-selective killing through the multi-targeting properties of natural products

PMID 18709883

How Melanotan II and PT-141 Work Both peptides act on the melanocortin receptor system, a group of receptors that regulate pigmentation, energy balance, and sexual function

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