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Its no wonder obesity is rising at such an alarming rate

Nature and Science of Sleep, 10, 421430

Blood was collected into vacutainer tubes containing EDTA by venipuncture, immediately placed on the ice, and centrifuged at 800 rpm for 15 min at room temperature

Despite this, some medical centers, including Cedars-Sinai, advise patients to discontinue GLP-1RA use one week before elective procedures

Thus, semaglutide likely contributes to immunometabolic remodeling of adipose tissue by reducing macrophage-mediated inflammation, shifting the macrophage phenotype toward the M2 (anti-inflammatory) state, and suppressing key inflammatory signaling pathways