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Co-localization studies revealed that many of the DNA damage sites that are occupied by -H2AX did not co-localize with pNPM1 to efficiently repair all the damaged sites, which could in turn lead to tumor cell death

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ArginaseII promotes melanoma migration and adhesion through enhancing hydrogen peroxide production and STAT3 signaling

Excitotoxicity causes massive calcium influx, activating calcium-dependent proteases and NOS, which rapidly trigger MMP-9 activation, leading to the swift degradation of tight junctions and the basement membrane (166)

the night before, then breaking my fast at noon, to be an easy yet highly effective way to fast during a typical workweek