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Neuronal GLP1R Mediates Liraglutides Anorectic but Not Glucose-Lowering Effect

Research published in the British Journal of Pharmacology demonstrated that molecular conjugation of B12 (specifically the corrin ring structure found in cyanocobalamin) with GLP-1 receptor agonists produced a compound that was not as readily absorbed into the brainstem areas responsible for triggering nausea

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She explains that a lot of people with obesity are obsessed with food and constantly triggered to crave it by their environment

10.1016/j.metabol.2021.154734 3 EbrahimN.ShakirovaK.DashinimaevE