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The review considers several mechanisms, including potential effects on amyloid-beta and pathologic tau burden, antioxidant defense, immune modulation, and regulation of circadian rhythms

It does this primarily by promoting angiogenesis, the formation of new blood vessels, which is critical for tissue repair

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This pathway involves the activation of tumor necrosis factor-alpha (TNF), followed by its receptor TNFR1 stimulation on the cell membrane

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