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In our study we are giving it to people who do not have dementia but are at risk through having high levels of the Alzheimers disease protein amyloid in-brain, said Dr Ivan Koychev of the University of Oxford

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Alanine replacement of Cys20, which was predicted to be the GSH binding site in the PtDHAR2 protein, eliminated DHAR activity 19

After excluding these outliers, mean baseline TMAO was 3.48 1.46 mol/L ( n = 30) (Figure 3)