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10.1126/scitranslmed.aah4477 18 BabiN.PeyrotF

I have had about 3 ECGs in my life because of this, all okay but sometimes I wonder if I have had a heart attack and just survived it

[2] The Phase 3a REDEFINE 2 trial then tested once-weekly CagriSema (cagrilintide 2.4 mg plus semaglutide 2.4 mg) against placebo in 1,206 adults with obesity and type 2 diabetes over 68 weeks, reporting a mean bodyweight change of 13.7% versus 3.4% for placebo

This is the only approved indication

This is of significant interest for studies on cellular senescence and the cellular response to genotoxic stress (e.g., UV radiation in keratinocyte cultures)