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B12 is fundamental to a number of important metabolic processes, including: Red blood cell formation Nervous system function Nutrient absorption Adrenal gland support Cognitive function and memory Brain cell regeneration DNA synthesis Mitochondrial metabolism Male and female reproductive health Because of its important role in the nervous system, severe B12 depletion over time can lead to irreversible neurological damage

J Ethnopharmacol 2016

Upon neutron irradiation, the COF not only released high-energy He and Li particles ( Figure 14C ) but also gradually released loaded imiquimod due to structural defects in the COF capsule ( Figure 14D ), promoting macrophage polarization and enhancing immune responses