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Euglycaemic DKA (where blood glucose may not be extremely elevated) can occur, particularly during illness, surgery, or significant dietary restriction

The blend's components have been investigated in combination protocols across dermal-research, tissue-repair, and combined-mechanism studies

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The SUMMIT trial took this further with tirzepatide, showing a 38% reduction in the composite of cardiovascular death or worsening heart failure (HR 0.62) in patients with HFpEF and obesity, along with a clinically meaningful 6.9-point improvement in KCCQ scores

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