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SOD and CAT are antioxidant enzymes necessary for the processing of ROS such as superoxide and hydrogen peroxide, and an increase in the transcription level of these enzymes indicates oxidative stress 49

A higher ratio indicates that your cells are well-equipped to handle oxidative stress and maintain metabolic function

Cohen et al., 2012), which is induced by dysregulation of redox conditions

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There is also biochemical evidence of E3 binding to the aminoacid terminal region of E1 terminal allowing for separation of a stable E1-E3 submolecular complex from the E2 core [49].Also attached are regulatory kinase and phosphatase units [50]