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Additionally, alterations in checkpoint control, such as the loss of cyclindependent kinase (CDK) inhibitors, enable uncontrolled cell cycle progression despite genomic instability, fostering survival under cytotoxic stress and promoting therapeutic resistance, heterogeneity, and relapse [93]

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Sep 2024 - Global pharmaceutical company Amneal Pharmaceuticals, Inc., and clinical-stage biopharmaceutical company Metsera, Inc., are accelerating next-generation medicines for obesity and metabolic diseases by joining forces with a portfolio of new weight loss medicines on efficient development and large-scale supply worldwide

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