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[123] and Myers [124]

Intranasal (a nasal spray) was the formulation tested in early trials and it did work, but was associated with more blood pressure side effects at effective doses

In developing regions, this financial barrier is even more pronounced, slowing market penetration despite growing obesity prevalence While efforts are underway to improve affordabilityincluding the introduction of generic formulations and price negotiations in certain marketsthe perception of GLP-1 therapies as premium, high-cost treatments can deter both patients and providers from widespread adoption Overcoming these challenges through the development of cost-effective alternatives, enhanced insurance support, and patient assistance programs will be vital for ensuring sustained and inclusive market growth in the GLP-1 receptor agonists obesity drugs market GLP-1 Receptor Agonists Obesity Drugs Market Scope The market is segmented on the basis of drug type, route of administration, application, and distribution channel

doi: 10.1186/2110-5820-1-37

Growth hormone (GH) and GH-releasing peptide-6 increase brain insulin-like growth factor-I expression and activate intracellular signaling pathways involved in neuroprotection