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Inhibitors of the ETC like resveratrol alter the electron flow rate changing the redox state of some site, lowering respiration rate, and raising ROS production in a given site of the ETC [32]

First of all we need to understand where the C rate comes from

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Gene expression analysis showed SFN-induced protection was associated with increased levels of NRF2 as well as decreased levels of toll-like receptor 4, a protein which upregulates the proinflammatory nuclear factor kappa (NF-kB) [107]