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Stacking with RF microneedling amplifies outcomes: at Perfect B in Doral, patients who combine GHK-Cu with Morpheus8 RF microneedling report visible collagen results 3 to 4 weeks earlier than GHK-Cu alone because microneedling creates direct channels for peptide uptake and simultaneously stimulates fibroblast activity

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The extent of the increase, which seems to be genotype dependent, was about 2-fold at 9 C after 4 months or up to 1.8-fold at 4 C after 7 months 151,152