Almost four decades later, Winfrey is part of a relatively new and ongoing cultural revolution in how doctors, patients, and families think about weight, and specifically, obesity as a chronic disease
The precise mechanism of action by which SGLT2 inhibitors act at this level remains to be defined, but it does not seem to depend entirely on weight loss.30,37 Unlike the myocardium, SGLT2 receptor expression has been found in adipose tissue samples from patients undergoing cardiac surgery.38 In these same clinical samples, dapagliflozin was found to induce higher glucose uptake, lower expression of inflammatory cytokines, and better differentiation of epicardial adipocytes
Bariatric surgery physically alters how and where the body processes food
Employer-sponsored coverage expansion Corporate coverage for GLP-1 medications shows measurable growth patterns
Kumar, P., Liu, C., Suliburk, J., Hsu, J