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[PUBMED Abstract] Pedace L, De Simone P, Castori M, et al.: Clinical features predicting identification of CDKN2A mutations in Italian patients with familial cutaneous melanoma

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The PI3K/AKT pathway is constitutively activated in a large fraction of EAOCs, often initiated by intrinsic structural alterations such as PTEN loss or PIK3CA activating mutations [25]

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