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reconstituted solution refrigerated at 28 C (35.646.4 F) for up to 14 days

First-line inavolisib/placebo + palbociclib + fulvestrant (Inavo/Pbo+Palbo+Fulv) in patients (pts) with PIK3CA-mutated, hormone receptor-positive, HER2negative locally advanced/metastatic breast cancer who relapsed during/within 12 months (mo) of adjuvant endocrine therapy completion: INAVO120 Phase III randomized trial additional analyses

Serious but rare effects may involve liver or kidney damage

10.26402/jpp.2018.3.11 5 Belosic HalleZ.VlainicJ.DrmicD.StrinicD.LueticK.SucicM.et al (2017)

Two of three subjects who had insulin resistance at baseline showed normal insulin responsiveness at the end of the study, and highly sensitive C-reactive protein (hs-CRP, a marker of systemic inflammation) improved by a median of 25% among participants who showed clinical psoriasis improvement