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Claudins, VEGF, Nrf2, Keap1, and Nonspecific Airway Hyper-Reactivity Are Increased in Mice Co-Exposed to Allergen and Acrolein

Featured Application Note Measuring GLP-1 Receptor Agonist Activity in Cells with the Lumit Insulin Immunoassay Imperial College London used the Lumit Insulin Immunoassay to differentiate the potency and activity of three GLP-1 receptor agonist drug candidates, demonstrating that the assay is well-suited for high-throughput metabolic disease drug discovery workflows

Some sub-analyses of large clinical trials suggest that GLP-1RA and sodium-glucose cotransporter 2 inhibitor combination therapy may provide more significant reductions in heart failure hospitalization and renal composite events than each alone

Compounded GLP-1 Options: Quality, Sourcing, and Regulatory Oversight Compounded GLP-1 medications (compounded semaglutide and tirzepatide) are prepared by licensed 503A compounding pharmacies under state pharmacy board oversight and FDA guidance

The metabolodiuretic promise of sodium-dependent glucose cotransporter 2 inhibition: the search for the sweet spot in heart failure