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Overexpression of phospholipid - hydroperoxide glutathione peroxidase in human dermal fibroblasts abrogates UVA irradiation - induced expression of interstitial collagenase/matrix metalloproteinase - 1 by suppression of phosphatidylcholine hydroperoxide - mediated NFkappaB activation and interleukin-6 release

Kim, M.-H., & Kim, H

Phase 2 trial (NEJM 2023) used a structured ramp to 12 mg/week but at trial doses of 8 mg and 12 mg, dropout from gastrointestinal events was substantial

Regulation of b cell fate, survival, and function by mitochondria and autophagy

Animal use and opportunities for reduction in carcinogenicity studies supporting approved new drug applications in the U.S., 20152019