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Benefits and Applications of GHK-Cu Skin Regeneration and Anti-Aging Effects One of the most well-known benefits of GHK-Cu is its ability to stimulate collagen synthesis and promote skin repair

Acknowledgements This project was supported by the National Natural Science Foundation of China (82272232, 82170775, 82370765, 82270802, 82100806, and 82300766) and the Open Project of Hubei Key Laboratory (2023KFZZ009)

GHK-Cu also improves the skin's ability to retain moisture, which contributes to a smoother, plumper complexion

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The latter was anchored by the 5 helix of G s (GH5) and formed rich contacts with TMs 2-7 and ICLs 1-3 (Supplementary Fig