Retatrutide achieved up to 24.2% mean weight loss after 48 weeks in individuals with obesity and 16.9% in those with T2D after 36 weeks
The SURMOUNT-1 trial evaluating tirzepatide showed more pronounced effects, with participants losing 15.0% (5 mg), 19.5% (10 mg), and 20.9% (15 mg) of body weight at 72 weeks
Check for medication quantity limits, because some countries impose limits on the medication you can bring (for example, a 30-day or 90-day supply) or require specific documentation for prescription drugs
Potential Long-Term Benefits: Research suggests that GLP-1 medications may have additional long-term benefits, including sustained weight loss maintenance and a reduced risk of weight regain
Goldfish kisspeptin: Molecular cloning, tissue distribution of transcript expression, and stimulatory effects on prolactin, growth hormone and luteinizing hormone secretion and gene expression via direct actions at the pituitary level