Cafestol may protect against diabetes-associated myocardial fibrosis, given that it mitigates against increased collagen synthesis, transforming growth factor-1 production, and Smad2/3 phosphorylation (seen on exposure to high glucose conditions) in rat cardiac fibroblasts [69]
IGF-1 is a highly anabolic peptide hormone responsible for: Muscle cell proliferation and repair Tendon and ligament regeneration Bone growth Glucose uptake in muscle cells Increased satellite cell activation Oral administration of MK-677 raised serum IGF-1 levels by over 60% in healthy adults without altering cortisol, insulin, or gonadotropin concentrations. Chapman et al., Clinical Pharmacology & Therapeutics This rise in IGF-1 is what leads to muscle growth, improved recovery, and increased physical resilience over time
Oncology 82(2):108-113, 2012
Improved range of motion at injury sites
Number of Sessions: Total cost depends on the complete treatment plan, including maintenance doses