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10.1016/s0021-9258(18)99105-2 606 ThompsonJ

In a 2-year trial involving patients with type 2 diabetes mellitus (T2DM) and high cardiovascular risk, more events of diabetic retinopathy complications occurred in patients treated with semaglutide 0.5 and 1 mg once weekly injections (3%) compared to placebo (1.8%)

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These include: Older adults on PPIs or H2 receptor antagonists Diabetic patients on metformin for a long time People with gut disorders that affect nutrient absorption Its important to check these individuals B12 levels to avoid deficiency