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A study in The Journal of Clinical Investigation demonstrated that glucagon infusion increases energy expenditure by 100 to 200 calories per day (4), and retatrutide replicates this effect through sustained receptor activation

Finally, in response to comments suggesting we adopt WAC or AWP based payment methodologies, we continue to believe that neither WAC nor AWP is an appropriate proxy to provide OPPS payment for average radiopharmaceutical acquisition costs and associated handling costs when manufacturers are not required to ( submit ASP data