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[1] [2] As a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, Mounjaro works by enhancing insulin secretion, suppressing glucagon release, slowing gastric emptying, and reducing appetite

[DOI] [PMC free article] [PubMed] [Google Scholar] 97.Sampath J., Adachi M., Hatse S., Naesens L., Balzarini J., Flatley R.M., Matherly L.H., Schuetz J.D

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This introductory phase allows the body to adjust to GLP-1, GIP, and glucagon receptor activation simultaneously