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2014 Mar;18(2):150-8

Inhibition of Nitro-oxidative stress Attenuates pulmonary and systemic injury induced by high-tidal volume mechanical ventilation

Adverse Reactions/Side Effects The following serious adverse reactions are discussed elsewhere in labeling: Cardiovascular Disorders [see Boxed Warning, Warnings and Precautions (5.1)] Malignant Neoplasms [see Boxed Warning, Warnings and Precautions (5.2)] 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice

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440 Surprisingly, although the appearance of Trop2 is necessary, a higher level of Trop2 does not necessarily result in a better response