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Combining CPAP with weight loss interventions, such as GLP-1 therapy, may reduce OSA severity, potentially decreasing the required CPAP pressure and improving comfort

History of pancreatitis: If you have a history of pancreatitis, an inflammation of the pancreas, you should avoid GLP-1 medications as they can potentially increase the risk of this condition

Its prolonged use can lead to dependence, meaning the brain will rely on this medication to produce adequate amounts of epinephrine and dopamine, she says

Additionally, it has been suggested that GIPR agonists and antagonists might target different CNS receptor populations, with evidence showing that acylated peptide GIPR agonists act on GABAergic neurons to further reduce food intake and body weight when combined with GLP-1R agonists in mice 39,40

The $50 monthly copay is significantly less than what patients without any insurance coverage for obesity drugs typically pay