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Generally, gastrointestinal adverse events were mild to moderate, mostly occurred during dose titration, and often resolved over time

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Wegovy prescribing information warns about several serious risks and adverse reactions associated with semaglutide use

More serious but less common risks include pancreatitis, gallbladder disease, acute kidney injury (particularly in the setting of dehydration from gastrointestinal symptoms), and hypoglycemia when used in combination with insulin or sulfonylureas

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